Vetenskapliga publikationer
Här listas några exempel på nyligen publicerade vetenskapliga artiklar från olika forskningsområden inom barncancer. Minst en av författarna till varje artikel har angett att de har finansiellt stöd från Barncancerfonden.
Om du vill synliggöra dina nya forskningsresultat, vänligen kontakta: forskningskommunikation@barncancerfonden.se
Publikationer
Pepich A, Tümmler C, Abu Ajamieh S, Treis D, Boje AS, Vellema Q, Tsea I, Åkerlund E, Seashore-Ludlow B, Shirazi Fard S, Kogner P, Johnsen JI, Wickström M. The ROCK-1/2 inhibitor RKI-1447 blocks N-MYC, promotes cell death, and emerges as a synergistic partner for BET inhibitors in neuroblastoma. Cancer Lett. 2024 Nov 28;605:217261. doi: 10.1016/j.canlet.2024.217261. Epub 2024 Sep 20. https://pubmed.ncbi.nlm.nih.gov/39307412/
Thombare K, Vaid R, Pucci P, Ihrmark Lundberg K, Ayyalusamy R, Baig MH, Mendez A, Burgos-Panadero R, Höppner S, Bartenhagen C, Sjövall D, Rehan AA, Dattatraya Nale S, Djos A, Martinsson T, Jaako P, Dong JJ, Kogner P, Johnsen JI, Fischer M, Turner SD, Mondal T. METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma. EMBO J. 2024 Nov 11. doi: 10.1038/s44318-024-00299-8. Epub ahead of print. https://pubmed.ncbi.nlm.nih.gov/39528654/
Larsson I, Held F, Popova G, Koc A, Kundu S, Jörnsten R, Nelander S. Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers. Nat Commun. 2024 Nov 9;15(1):9699. doi: 10.1038/s41467-024-53954-3. https://pubmed.ncbi.nlm.nih.gov/39516198/
Pergert P, Molewijk B, Bartholdson C. Positioning Ethics When Direct Patient Care is Prioritized: Experiences from Implementing Ethics Case Reflection Rounds in Childhood Cancer Care. HEC Forum. 2024 Nov 2. doi: 10.1007/s10730-024-09541-6. Epub ahead of print. https://pubmed.ncbi.nlm.nih.gov/39487914/
Maya-González C, Tettamanti G, Taylan F, Skarin Nordenvall A, Sejersen T, Nordgren A. Cancer Risk in Patients With Muscular Dystrophy and Myotonic Dystrophy: A Register-Based Cohort Study. Neurology. 2024 Oct 22;103(8):e209883. doi: 10.1212/WNL.0000000000209883. Epub 2024 Sep 19. https://pubmed.ncbi.nlm.nih.gov/39298705/
Zhou O, Harila A, Hovén E, Lönnerblad M. Educational outcomes school year nine in children treated for acute lymphoblastic leukemia: A nationwide registry-based study from Sweden. Int J Cancer. 2024 Oct 19. doi: 10.1002/ijc.35231. Epub ahead of print. https://pubmed.ncbi.nlm.nih.gov/39425561/
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray JK, Ray C, Berenguer C, Kumari P, Bech JJ, Braun T, Ianni A, Tischfield JA, Serrano L, Esteller M, Sardina JL, De La Torre C, Sigvardsson M, Vazquez BN, Vaquero A. A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5. Nat Immunol. 2024 Oct 18. doi: 10.1038/s41590-024-01995-7. Epub ahead of print. https://pubmed.ncbi.nlm.nih.gov/39424985/
Sørensen GV, Mogensen H, Holmqvist AS, Kenborg L, Pedersen C, Nielsen TT, Talbäck M, Erdmann F, Ifversen M, Feychting M, Schmiegelow K, Heyman MM, Winther JF, Hasle H, Frederiksen LE. Psychiatric disorders among survivors of childhood acute lymphoblastic leukemia in Denmark and Sweden. Pediatr Blood Cancer. 2024 Dec;71(12):e31361. doi: 10.1002/pbc.31361. Epub 2024 Oct 7. https://pubmed.ncbi.nlm.nih.gov/39375822/
Chen Y, Su Y, Cao X, Siavelis I, Leo IR, Zeng J, Tsagkozis P, Hesla AC, Papakonstantinou A, Liu X, Huang WK, Zhao B, Haglund C, Ehnman M, Johansson H, Lin Y, Lehtiö J, Zhang Y, Larsson O, Li X, de Flon FH. Molecular Profiling Defines Three Subtypes of Synovial Sarcoma. Adv Sci (Weinh). 2024 Nov;11(41):e2404510. doi: 10.1002/advs.202404510. Epub 2024 Sep 10. https://pubmed.ncbi.nlm.nih.gov/39257029/
Nagarajan D, Parracho RT, Corujo D, Xie M, Kutkaite G, Olsen TK, Rubies Bedos M, Salehi M, Baryawno N, Menden MP, Chen X, Buschbeck M, Mao Y. Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma. J Clin Invest. 2024 Sep 10;134(21):e175310. doi: 10.1172/JCI175310. https://pubmed.ncbi.nlm.nih.gov/39255035/
Ek T, Ibrahim RR, Vogt H, Georgantzi K, Träger C, Gaarder J, Djos A, Rahmqvist I, Mellström E, Pujol-Calderón F, Vannas C, Hansson L, Fagman H, Treis D, Fransson S, Österlund T, Chuang TP, Verhoeven BM, Ståhlberg A, Palmer RH, Hallberg B, Martinsson T, Kogner P, Dalin M. Long-Lasting Response to Lorlatinib in Patients with ALK-Driven Relapsed or Refractory Neuroblastoma Monitored with Circulating Tumor DNA Analysis. Cancer Res Commun. 2024 Sep 1;4(9):2553-2564. doi: 10.1158/2767-9764.CRC-24-0338. https://pubmed.ncbi.nlm.nih.gov/39177282/
Fermér J, Jalnäs J, Abrahamsson J, Borssen M, Donnér I, Henriksson L, Heyman M, Holmqvist AS, Valind A, Vogt H, Wretman A, Zhou O, Harila A, Ranta S. Haemostasis during early treatment of childhood acute lymphoblastic leukaemia with the ALLTogether protocol. Acta Paediatr. 2024 Dec;113(12):2676-2678. doi: 10.1111/apa.17398. Epub 2024 Aug 27. https://pubmed.ncbi.nlm.nih.gov/39190328/
Giertz M, Aarnivala H, Wilk Michelsen S, Björklund C, Englund A, Grönroos M, Hjalgrim LL, Huttunen P, Niinimäki T, Penno E, Pöyhönen T, Raittinen P, Ranta S, Svahn JE, Törnudd L, Niinimäki R, Harila A. Symptomatic osteonecrosis in children treated for Hodgkin lymphoma: A population-based study in Sweden, Finland, and Denmark. Pediatr Blood Cancer. 2024 Nov;71(11):e31250. doi: 10.1002/pbc.31250. Epub 2024 Aug 14. https://pubmed.ncbi.nlm.nih.gov/39140964/
Cui Y, Harteveld F, Ba Omar HAM, Yang Y, Bjarnason R, Romerius P, Sundin M, Norén Nyström U, Langenskiöld C, Vogt H, Henningsohn L, Frisk P, Vepsäläinen K, Petersen C, Mitchell RT, Guo J, Alves-Lopes JP, Jahnukainen K, Stukenborg JB. Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients. Hum Reprod Open. 2024 Aug 13;2024(3):hoae049. doi: 10.1093/hropen/hoae049. https://pubmed.ncbi.nlm.nih.gov/39188568/